| Top 2016 South Dakota Presidential Democrat Counties by Percentage |
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| Rank | Region | Votes | % of Votes |
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| 1 | Shannon County | 2,504 | 86.5 | | 2 | Todd County | 1,505 | 70.8 | | 3 | Buffalo County | 296 | 60.4 | | 4 | Dewey County | 887 | 52.0 | | 5 | Clay County | 2,608 | 51.4 | | 6 | Corson County | 535 | 45.5 | | 7 | Ziebach County | 352 | 46.0 | 
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