| Top 2016 Florida Presidential Republican Counties by Percentage |
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| Rank | Region | Votes | % of Votes |
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| 1 | Holmes County | 7,476 | 87.9 | | 2 | Lafayette County | 2,795 | 82.8 | | 3 | Dixie County | 5,822 | 80.8 | | 4 | Baker County | 10,294 | 81.5 | | 5 | Union County | 4,567 | 80.2 | | 6 | Gilchrist County | 6,740 | 80.1 | | 7 | Calhoun County | 4,647 | 76.6 | 
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