The population of De Soto county is estimated at 35,925. In 2017 there were 368 births and 306 deaths in De Soto county. De Soto county has 4,180 housing units that are owned with a mortgage or a loan, 4,057 that are owned free and clear and 3,208 that are renter occupied.

  The good residents of De Soto County filed 12,270 federal tax returns in 2017. This amount represents 0.1% of all Florida filings and 0.008% of the entire nation. De Soto had a combined total federal tax liability of $64,240,000 on earned income of $463,839,000. Other notable statistics from De Soto County were 180 unemployment claims which collected a total of $592,000 and 1,010 charitable contributions valued at $5,868,000. 1,120 filings from De Soto County paid a combined total of $3,975,000 in property taxes and 860 filings paid $5,845,000 on mortgage interest costs.

  In 2010 De Soto county had 57 religious congregations with an estimated 14,282 members.
11.5% of the De Soto population has a college level Bachelors degree or higher. 29.5% have less than a highschool diploma level education.

About 30% of DeSoto County voted in the presidential election of 2016. This represents an increase from the 2012 election by 898 votes.
At $37,342 the median income is 71.0% of the Florida average. An estimated 608 people claimed to be unemployed last year in De Soto, the equivalant of around 4.4% of the county population. This represents a decrease in the level of unemployment from the previous year's value of 5.3%.

Top 15 Industries in De Soto County.
Total # Employed	Industry Job Type
1,009	Health care and social assistance
1,003	Retail trade
917	Transportation and warehousing
402	Accommodation and food services
347	Food services and drinking places
235	Manufacturing
232	Limited-service restaurants
186	Motor vehicle and parts dealers
161	Finance and insurance
149	Grocery stores
148	Ambulatory health care services
126	Supermarkets and other grocery (except convenience) stores
114	Professional, scientific, and technical services
95	Real estate and rental and leasing
86	Offices of physicians

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