The population of Saint Francois county is estimated at 66,393. In 2017 there were 683 births and 751 deaths in Saint Francois county. Saint Francois county has 10,675 housing units that are owned with a mortgage or a loan, 5,727 that are owned free and clear and 7,579 that are renter occupied.

  The upstanding residents of Saint Francois County filed 25,840 federal tax returns in 2017. This amount represents 0.9% of all Missouri filings and 0.017% of the entire nation. Saint Francois had a combined total federal tax liability of $160,054,000 on earned income of $1,158,840,000. Other notable statistics from Saint Francois County were 1,040 unemployment claims which collected a total of $3,146,000 and 3,350 charitable contributions valued at $16,232,000. 4,020 filings from Saint Francois County paid a combined total of $6,836,000 in property taxes and 3,390 filings paid $20,179,000 on mortgage interest costs.

  In 2010 Saint Francois county had 126 religious congregations with an estimated 28,737 members.
13.3% of the Saint Francois population has a college level Bachelors degree or higher. 16.8% have less than a highschool diploma level education.

Approximately 37% of Saint Francois County voted in the presidential election of 2016. This represents an increase from the 2012 election by 2,124 votes.
At $41,708 the median income is 78.0% of the Missouri average. An estimated 1,163 people claimed to be unemployed last year in Saint Francois, the equivalant of around 4.4% of the county population. This represents a decrease in the level of unemployment from the previous year's value of 5.5%.

Top 15 Industries in Saint Francois County.
Total # Employed	Industry Job Type
5,279	Health care and social assistance
3,421	Retail trade
1,824	Hospitals
1,802	Accommodation and food services
1,707	Food services and drinking places
1,687	Restaurants and other eating places
1,474	Manufacturing
1,332	Ambulatory health care services
1,161	Nursing and residential care facilities
974	Administrative and support and waste management and remediation services
962	Social assistance
952	Administrative and support services
933	Finance and insurance
895	Limited-service restaurants
734	Full-service restaurants

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