The population of De Soto county is estimated at 175,545. In 2017 there were 2,169 births and 1,360 deaths in De Soto county. De Soto county has 35,201 housing units that are owned with a mortgage or a loan, 8,664 that are owned free and clear and 13,883 that are renter occupied.

  The good residents of De Soto County filed 80,600 federal tax returns in 2017. This amount represents 6.6% of all Mississippi filings and 0.054% of the entire nation. De Soto had a combined total federal tax liability of $621,685,000 on earned income of $4,398,387,000. Other notable statistics from De Soto County were 1,410 unemployment claims which collected a total of $4,448,000 and 22,990 charitable contributions valued at $137,217,000. 21,690 filings from De Soto County paid a combined total of $41,926,000 in property taxes and 20,800 filings paid $139,162,000 on mortgage interest costs.

  In 2010 De Soto county had 180 religious congregations with an estimated 85,106 members.
23.5% of the De Soto population has a college level Bachelors degree or higher. 10.6% have less than a highschool diploma level education.

Approximately 36% of DeSoto County voted in the presidential election of 2016. This represents a decrease from the 2012 election by 4 votes.
At $66,125 the median income is 151.7% of the Mississippi average. An estimated 3,344 people claimed to be unemployed last year in De Soto, the equivalant of around 3.8% of the county population. This represents a decrease in the level of unemployment from the previous year's value of 4.2%.

Top 15 Industries in De Soto County.
Total # Employed	Industry Job Type
7,957	Retail trade
6,498	Accommodation and food services
5,719	Food services and drinking places
5,623	Restaurants and other eating places
5,597	Health care and social assistance
5,534	Transportation and warehousing
5,081	Administrative and support and waste management and remediation services
4,984	Administrative and support services
4,225	Employment services
3,906	Warehousing and storage
3,453	Manufacturing
2,840	Wholesale trade
2,741	Limited-service restaurants
2,721	Full-service restaurants
2,174	Ambulatory health care services

In 2018 the average price reduction was 2.05% in DeSoto County (averaging across 5 zip codes; 38632, 38671, 38654, 38637 and 38672).

In 2018 10.46% of listings in De Soto County (averaging across 6 zip codes a sample of which are; 38637, 38671, 38654, 38672 and 38632) dropped their price.

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