The population of Panola county is estimated at 23,440. In 2017 there were 269 births and 275 deaths in Panola county. Panola county has 3,231 housing units that are owned with a mortgage or a loan, 3,881 that are owned free and clear and 2,159 that are renter occupied.

  The upstanding residents of Panola County filed 9,660 federal tax returns in 2017. This amount represents 0.1% of all Texas filings and 0.006% of the entire nation. Panola had a combined total federal tax liability of $78,418,000 on earned income of $504,485,000. Other notable statistics from Panola County were 530 unemployment claims which collected a total of $3,334,000 and 1,530 charitable contributions valued at $11,209,000. 1,520 filings from Panola County paid a combined total of $4,485,000 in property taxes and 1,110 filings paid $7,468,000 on mortgage interest costs.

  In 2010 Panola county had 71 religious congregations with an estimated 11,628 members.
14.7% of the Panola population has a college level Bachelors degree or higher. 15.1% have less than a highschool diploma level education.

About 44% of Panola County voted in the presidential election of 2016. This represents an increase from the 2012 election by 192 votes.
At $48,971 the median income is 82.7% of the Texas average. An estimated 564 people claimed to be unemployed last year in Panola, the equivalant of around 5.5% of the county population. This represents a decrease in the level of unemployment from the previous year's value of 7.2%.

Top 15 Industries in Panola County.
Total # Employed	Industry Job Type
1,662	Transportation and warehousing
1,556	Truck transportation
1,534	Specialized freight trucking
939	Retail trade
905	Manufacturing
653	Health care and social assistance
419	Accommodation and food services
365	Food services and drinking places
339	Restaurants and other eating places
282	Administrative and support and waste management and remediation services
224	Administrative and support services
224	Nursing and residential care facilities
211	Food and beverage stores
206	Professional, scientific, and technical services
194	Limited-service restaurants

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