The population of Karnes county is estimated at 15,264. In 2017 there were 182 births and 138 deaths in Karnes county. Karnes county has 1,194 housing units that are owned with a mortgage or a loan, 1,997 that are owned free and clear and 1,272 that are renter occupied.

  The gracious residents of Karnes County filed 5,620 federal tax returns in 2017. This amount represents 0.0% of all Texas filings and 0.004% of the entire nation. Karnes had a combined total federal tax liability of $111,012,000 on earned income of $423,308,000. Other notable statistics from Karnes County were 220 unemployment claims which collected a total of $1,172,000 and 590 charitable contributions valued at $7,089,000. 600 filings from Karnes County paid a combined total of $2,253,000 in property taxes and 360 filings paid $2,557,000 on mortgage interest costs.

  In 2010 Karnes county had 40 religious congregations with an estimated 8,185 members.
13.7% of the Karnes population has a college level Bachelors degree or higher. 24.4% have less than a highschool diploma level education.

About 27% of Karnes County voted in the presidential election of 2016. This represents an increase from the 2012 election by 5 votes.
At $48,708 the median income is 82.3% of the Texas average. An estimated 224 people claimed to be unemployed last year in Karnes, the equivalant of around 3.5% of the county population. This represents a decrease in the level of unemployment from the previous year's value of 4.9%.

Top 15 Industries in Karnes County.
Total # Employed	Industry Job Type
479	Retail trade
437	Health care and social assistance
427	Accommodation and food services
354	Food services and drinking places
352	Restaurants and other eating places
284	Manufacturing
249	Transportation and warehousing
193	Full-service restaurants
176	Nursing and residential care facilities
176	Nursing care facilities (skilled nursing facilities)
162	Specialized freight trucking
159	Limited-service restaurants
126	Gasoline stations
116	Plastics and rubber products manufacturing
116	Plastics product manufacturing

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